Can Polygonum multiflorum cause liver injury?

Can Polygonum multiflorum cause liver injury? Can Polygonum multiflorum Thunb cause liver injury?

ancient novels often have the plot of eating Shouwu black hair. Radix Polygoni Multiflori can treat or assist in the treatment of hypertension, hyperlipidemia, bone hyperplasia, constipation, alopecia and other diseases, but with the increasing use, its safety has become the focus. Recently, the State Food and Drug Administration (CFDA) released the latest adverse reaction notice, suggesting that Polygonum multiflorum has the risk of causing liver injury.

the processed Radix Polygoni Multiflori has the functions of tonifying liver and kidney, benefiting essence and blood, and black hair. The raw Radix Polygoni Multiflori can detoxify and defecate, but it has certain toxicity, so it is not recommended to use it on its own. The report suggests that liver injury may be caused by improper selection of Radix Polygoni Multiflori, eating unprocessed raw Radix Polygoni Multiflori, taking a large amount of Radix Polygoni Multiflori for a long time and individual differences. If the patient’s liver function is normal in the past, and there are symptoms such as skin and sclera yellow staining, urine yellow, anorexia, loss of appetite, and general fatigue during medication, it is recommended to check bilirubin and transaminase in time. If it increases, it indicates that drug-induced liver injury may occur. The drug should be stopped immediately according to the doctor’s advice.

generally speaking, the liver injury caused by Radix Polygoni Multiflori is reversible and can recover after a period of time. In order to prevent liver injury caused by Radix Polygoni Multiflori, it is not recommended for healthy people to take Radix Polygoni Multiflori blindly; After medication, we should pay attention to observe the symptoms and see a doctor in time in case of suspicious performance; Avoid using it with other drugs that have great influence on liver; Patients with liver dysfunction or history of liver injury with other drugs should be cautious.

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